EXPLICIT MOLECULAR DYNAMICS SIMULATION STUDIES TO DISCOVER NOVEL NATURAL COMPOUND ANALOGUES AS MYCOBACTERIUM TUBERCULOSIS INHIBITORS

Explicit molecular dynamics simulation studies to discover novel natural compound analogues as Mycobacterium tuberculosis inhibitors

Tuberculosis (TB) in one of the dreadful diseases present globally.This is caused by Mycobacterium tuberculosis.Mycobacterium tuberculosis dethiobiotin synthetase (MtDTBS) is an essential enzyme in biotin biosynthesis and is an ideal target to design and develop novel inhibitors.In order to effectively combat this disease six natural compound (bute

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Identifying functional network changing patterns in individuals at clinical high-risk for psychosis and patients with early illness schizophrenia: A group ICA study

Although individuals at clinical high risk (CHR) for psychosis exhibit a psychosis-risk syndrome involving attenuated forms of the positive symptoms typical of schizophrenia (SZ), it remains unclear whether their resting-state brain intrinsic functional networks (INs) show attenuated or qualitatively distinct patterns of functional dysconnectivity

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Weak Positional Games on Hypergraphs of Rank Three

In a weak positional game, two players, Maker and Breaker, alternately claim vertices of a hypergraph until either Maker wins by getting a complete edge or all vertices are taken without this happening, a Breaker win.For the class of almost-disjoint hypergraphs of White Noise Machines rank three (edges with up to three vertices only and edge-inters

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